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In our lab, we want to understand the molecular mechanisms of centriole and cilia function, how they are assembled and how they are regulated, in health and disease. Because centrioles and cilia can function as signalling hubs, and host a number of signal transduction molecules and receptors, our research aims at understanding how centrioles and cilia may affect signal transduction pathways that control cellular functions, such as polarity, morphogenesis, and metabolism.