Welcome!

Cilia are sensory antenna, emerging from the cell surface, that detect mechanical and chemical stimuli from the environment. Centrioles function as templates for cilia, and they organize in a beautiful nine-fold symmetry.

In our lab, we want to understand the molecular mechanisms of centriole and cilia assembly, how these structures function as signaling organelles, and how this regulation is altered at the onset of disease. Centrioles and cilia host a number of signal transduction molecules. But the role of cilia as signaling hubs is only starting to be unraveled. Our research aims to understand how centrioles and cilia control physiological functions, such as polarity, morphogenesis, and metabolism through their effects on signal transduction.